PLATELET-RICH FIBRIN MATRIX (PRFM)
We are now offering the next generation of blood concentrate and platelet therapy. Microneedling alone will increase collagen, but in combination with YOUR OWN growth factors in higher concentrations (PRFM), we can induce extra collagen, new cells and elastin fibers, which creates an overall improvement in skin hydration, tone, and texture. This treatment harnesses the body’s natural healing process to provide effective rejuvenation from the inside out.
Human blood consists of several components, including platelet rich plasma (PRP) and platelet rich fibrin (PRF) which are full of growth factors that repair damage in the body. PRP and PRF have long been used in sports medicine, dentistry, and pain management to accelerate healing. In a PRP or PRF procedure, a medical professional utilizes the patient’s own palsma by administering a blood draw and then using a centrifuge to separate the blood components. Improve complexion or reverse the signs of aging. Microneedling uses tiny sterile needles to inject the PRFM into a targeted area. This method is ideal because microneedling on it’s own has regenerative benefits.
The Selphyl® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a small sample of blood at the patient point of care. Many PRP systems require operator skill, have varying results and have extensive contamination with red blood cells and white blood cells. Selphyl® removes virtually all contaminating cells and is independent of operator technique. PRP is converted to PRFM through a controlled process, creating a scaffold that serves to protect and preserve platelets. Think of Selphyl® PRFM as the next generation PRP. The procedure builds collagen, treats fine lines and wrinkles, acne scars, stretch marks, pore size and surgical scars.
The Power of Platelets
Platelets and other components in human blood migrate to a site of injury. Platelets are known to release a variety of growth factors that respond to tissue injury, where they initiate and promote healing. By concentrating platelets at the site of injury, physicians have the potential to enhance the body’s natural capacity for healing.
What is Platelet-Rich Plasma (PRP)?
PRP, by definition refers to platelets in plasma, where the platelet concentration is generally considered to be twice the normal concentration in whole blood. Nowhere in the definition of PRP is there a description for including red blood cells (RBC) or white blood cells (WBC) – in fact, these cells should be removed as much as possible from a PRP preparation. Some kits that tout high platelet concentrations often do so at the expense of having contaminating RBCs or WBCs – these cells are known to have inflammatory and catabolic effects – just the opposite of the desired effect. If the PRP in the syringe has any tinge of pink or red, it is mostly likely that you are injecting a preparation that has RBC contamination. The ideal PRP solution will be a golden, straw-like color.
What is SELPHYL® PRFM?
The Selphyl® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a small sample of blood at the patient point of care. Many PRP systems require operator skill, have varying results and have extensive contamination with red blood cells and white blood cells. Selphyl® removes virtually all contaminating cells and is independent of operator technique. PRP is converted to PRFM through a controlled process, creating a scaffold that serves to protect and preserve platelets. Think of Selphyl® PRFM as the next generation PRP.
How is SELPHYL® PLATELET-RICH FIBRIN MATRIX (PRFM) Different?
The Selphyl® System is a completely closed system and can convert PRP to PRFM with the addition of a precise amount of calcium chloride, which initiates the conversion of fibrinogen to fibrin, as part of the clotting cascade. The fibrin matrix serves as a three dimensional scaffold to maintain the platelets at the site of injection. The scaffold also serves to protect the platelets so their release of growth factors can be sustained over a longer period of time.
THE MAIN ADVANTAGES & BENEFITS INCLUDE:
VISUAL GUIDE TO QUALITY
COMPLETELY CLOSED SYSTEM
FIBRIN MATRIX SCAFFOLD
SUSTAINED GF RELEASE
EXTENSIVE SAFETY PROFILE
OVER 150K PATIENTS TREATED
The idea of SELPHYL® PRFM is that it treats the main cause of skin aging by producing new cells and collagen. SELPHYL® PRFM uses your natural biology to rejuvenate and increase the volume of skin. As soon as SELPHYL® PRFM is administered, growth factors are released into the layers of your skin. SELPHYL® PRFM uses your natural biology to address skin defects and volume loss. After the administration of SELPHYL® PRFM, patients have seen visible improvement with long lasting effects. Pronounced effects typically occur in approximately three weeks.
Where the cosmetic procedure can be applied…
- Glabella Line
- Forehead Area
- Periorbital Lines
- Cheek Augmentation
- Nasolabial Folds
- Smile Lines
- Acne Scar
- Vermilion Border
- Marionette Lines
Prior to treatment, a topical numbing cream is applied for about 30 to 40 minutes. Once the area is numb, the cream is removed and the skin is prepped for treatment.
To develop a PRFM preparation, blood is drawn from the patient. The sample is placed in a sterile chamber and spun in a centrifuge to separate the platelets from the other blood cells. PRFM is first injected into desired areas.
After the facial injections are performed the remaining plasma is applied topically to the entire face during the microneedling procedure using Rejuvapen™ Collagen Induction Therapy. The microneedling procedure itself takes about 20 minutes to complete.
The Rejuvapen is a remarkable, non-laser, non-surgical treatment that causes skin to stimulate collagen production and fresh, new tissue. Skin tightens; wrinkles, fine lines, scarring, and hyperpigmentation significantly diminish; pores become finer; and the overall health and circulation of the skin is improved. As microneedling enhances the production of collagen, with the introduction of your body’s own platelet rich plasma and growth factors, this process is dramatically increased for advanced anti-aging effects. The treatment can help reverse sun damage, improve the appearance of acne scars, fine lines, wrinkles and hyper-pigmentation. An overall healthier appearance of the skin will occur. We recommend a series of 3 treatments to be performed 6 weeks apart.
HOW LONG DOES THE PROCEDURE TAKE?
The entire procedure takes about 90 minutes to perform including injections and microneedling.
HOW MANY TREATMENTS ARE NEEDED?
The number of treatments needed depends on each individual patient, the desired outcome, and your skin’s condition however we generally recommend a series of 3 treatments done 6 weeks apart.
IS THE TREATMENT PAINFUL?
Unlike other products that are acidic (low pH), Selphyl® PRFM has close to physiologic pH. There may be some temporary discomfort during the injections. Like all injection procedures, one can experience occasional redness and bruising immediately following the treatment that resolves quickly. Numbing cream will be called into your pharmacy and should be applied 45 minutes prior to service for minimizing the discomfort of the microneedling treatment.
ARE THERE ANY SIDE EFFECTS?
There have been no known side effects associated with Selphyl® reported to date. As with any injectable procedure, some patients may experience some mild and temporary irritation, swelling, bruising, itching, discoloration or tenderness at the injection site.
As for the Microneedling portion of the treatment, there is little to no downtime. You can expect some redness and minor swelling following the treatment. We recommend that you do not wash your skin or apply additional products the day of but may resume with gentle skin care the following day. Minimize sun exposure and wear sunscreen for 7 days post procedure.
CAN ANYONE BE ALLERGIC TO SELPHYL®?
There is virtually no risk of allergic reaction. The Selphyl® PRFM System is used to rapidly collect and isolate a patient’s own PRFM for injection and contains no animal or synthetic products.